The 25th Annual Meeting of the China Association for Science and Technology raised 10 cutting-edge scientific questions, of which the fourth major problem was “Will nonlinear effects change with scale?” This paper focuses on nonlinear effects (phenomena) in the engineering field, as well as some nonlinear factors in the modeling of engineering, including nonlinearities of structural or material deformation, non-smooth systems, shaft cracks, nonlinear forces of sliding and rolling bearings, structural hysteretic nonlinearity, circuit nonlinearity, flow-induced vibration, etc., providing some references for exploring this problem.